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Lead Automation Engineer, Autonomous Lab Science & Technology

Genentech · South San Francisco, CA

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Level
Manager
Team
Controls
Base pay
$169k–$314k
Degree
Required
Industry
Pharma & life sciences
Posted
7 days ago

The role in 30 seconds

A management controls role at Genentech (pharma & life sciences) in South San Francisco, CA.

They ask for
degree required
Tools it names
Robotics, Automation
Base pay
$169k–$314k

Read from the posting. The full description is below.

From the plant jobs report · week of November 2, 2026

Controls Engineer roles in California: typical posted base $127k–$179k. This one lists $169k–$314k.

Median of the low and high ends of 66 live postings that list pay, out of 122 controls engineer openings in California, read from manufacturers' own careers sites.

California plant jobs report →Pay by team and state →What moves pay →

How this role compares

Against 121 other live controls postings in California.

Base pay
About 60% above similar roles

Typical $123k–$179k, from 62 postings that list pay.

Experience asked
Not stated

Similar roles usually ask 5+ years.

Skills these teams ask for most

  • ✓ Automation 67%
  • ✓ Robotics 44%
  • PLC 43%
  • ✓ Python 34%
  • Validation (IQ/OQ/PQ) 34%

✓ = this posting asks for it too. % = share of similar postings that mention it.

At a glance

Pulled from the posting text. If it's not listed here, the posting didn't say.

How to get in at this plant

Five moves over a week or two. The first one takes ten minutes.

  1. 1

    Pick 2–3 people on the Controls team at Genentech

    Engineers who joined in the last year or two reply the most. Use the team search on this page to find them.

  2. 2

    Send a short, curious note

    One real question about their work. No favors yet. Each person gets a different note, written for this role.

  3. 3

    Turn a reply into a short call

    Questions worth asking about this team:

    • What does a normal week look like on your team?
    • How did you land the job? What stood out in your interviews?
  4. 4

    Apply with someone vouching for you

    If the call went well, ask whether they’d pass your résumé to the hiring manager. Send your résumé link, apply that day, and let them know.

  5. 5

    Bring proof to the interview

    One page of before-and-after numbers from projects you led: scrap, OEE, cycle time, cost. Plant managers hire on results.

This plant: Genentech in South San Francisco

3 other open roles at this site.

Full description from GenentechAs posted on their careers site.Show

requirements

into executable laboratory processes and scalable physical automation platforms. The individual in this role would own how scientific

requirements

are technically realized through robotics, instrumentation, instrument-control software, execution-layer interfaces, and integrated laboratory systems. You also partner with Lab Operations from design through operational acceptance so new capabilities are engineered for autonomous, reliable, and supportable routine use.

Key Responsibilities

  • ◆Physical Platform Architecture: Own the end-to-end architecture of the physical execution platform, from instruments and robotic work cells to integrated, increasingly unattended laboratory systems. Serve as the technical design authority for robotics, scientific instrumentation, instrument-control software, execution-layer interfaces, and reusable platform patterns.
  • ◆Scientific Workflow Translation & Execution Design: Partner with Science & Technology Project Leaders and scientific SMEs to convert defined scientific

requirements

and acceptance criteria into automatable unit operations, equipment requirements, sample and material flows, execution sequences, control points, and exception states. Identify technical constraints and recommend workflow adaptations required for robust automated execution.

  • ✓AI-to-Execution & Data Interfaces: Partner with CS CoE to define the boundary between digital orchestration and physical execution: how digitally specified experiments become machine-executable actions and how instrument outputs, system state, sample identity, metadata, and execution context return to downstream systems. Own the physical-platform interface and device

requirements

while CS CoE owns the corresponding higher-level AI, informatics, and orchestration capabilities.

  • ✓Build, Commission & Technical Verification: Lead technical selection, integration, commissioning, and verification of robotics, liquid handlers, scientific instruments, schedulers, and control layers. Demonstrate that new platforms satisfy defined technical and scientific

requirements

before they progress to operational acceptance.

  • ✓Autonomy, Operability & Operational Handoff: Engineer the capabilities required for unattended execution, including state awareness, observability, exception detection, automated recovery, safe-stop behavior, and appropriate human escalation. Design for maintainability and serviceability, jointly define operational-readiness criteria with Lab Operations, and support formal acceptance into routine operations. After acceptance, remain the technical design authority for material architecture changes, new capabilities, and systemic technical limitations; Lab Operations owns routine execution, monitoring, maintenance, incident response, and established recovery procedures.
  • ✓Technical Leadership & Reuse: Lead complex technical problem solving, architecture and design reviews, and the development of reusable engineering standards. Mentor engineers and direct contractors, vendors, and system integrators while communicating technical tradeoffs clearly across science, software, automation, facilities, and operations.

requirements

through commissioning, technical verification, and scientific acceptance.

  • ✓Reusable Engineering Standards: Common patterns for instrument and robotic integration, execution state, data capture, observability, error handling, recovery, and deployment across the organization.
  • ✓Operational Readiness & Transfer: Joint readiness criteria and handoff packages that enable Lab Operations to formally accept new systems into reliable routine use, with clear post-deployment ownership for operations versus engineering changes.

Who you are

  • ✓Education & Experience: Bachelor's or advanced degree in engineering, computer science, life sciences, or a related discipline, with significant experience in laboratory automation and systems integration.
  • ✓Automation & Systems Expertise: Deep experience designing, programming, integrating, and deploying laboratory automation platforms such as Hamilton, Tecan, Agilent, HighRes, Opentrons, robotic arms, schedulers, or comparable technologies.
  • ✓Software & Integration Fluency: Strong Python and API-integration skills, with experience connecting instruments to schedulers, databases, message brokers, LIMS/ELN, or other scientific software systems.
  • ✓End-to-End Delivery: Demonstrated ownership of greenfield automation platforms from architecture and vendor selection through commis
Show full description ↓

The Position

The Position

A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche.

Advances in AI, data, robotics, and laboratory automation are transforming drug discovery and development. The Roche Autonomous Lab Accelerator brings together gRED, pRED, PT, and the Computational Sciences Center of Excellence (CS CoE) to build closed-loop Lab-in-the-Loop capabilities that connect scientific intent, digital design, experimental execution, and high-quality data generation.

The Opportunity

You are the technical lead for Lab Automation within Automation Science & Technology and the owner of the physical platform architecture for the Roche Autonomous Lab Accelerator. This role reports to the Head, Automation Science & Technology, Autonomous Lab Accelerator.

Working closely with Science & Technology Project Leaders, scientific SMEs, Lab Operations, and Lab Automation Informatics partners, you translate defined scientific workflow

Key Deliverables

  • •Physical Platform Reference Architecture: A scalable architecture for the Accelerator physical execution layer and clearly defined interfaces with CS CoE systems.
  • •Integrated Autonomous Capabilities: Priority laboratory automation platforms delivered from defined scientific

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