Principal NPI Manufacturing Engineer, Electromechanical Systems

TransMedics · Andover, MA

Level: Senior
Team: Reliability
Base pay: $147k–$184k
Experience asked: 10+ years
Industry: Medical devices
Posted: 4 days ago

The role in 30 seconds

A senior reliability role at TransMedics (medical devices) in Andover, MA. Coordinate, identify, develop, and implement advanced manufacturing processes to ensure production capacity, efficiency, cost-effectiveness, product quality, and adherence to applicable regulatory requirements.

They ask for: 10+ years
Tools it names: Root cause, SPC, FMEA, MSA / Gage R&R, FDA / GMP, Validation (IQ/OQ/PQ)
Base pay: $147k–$184k

Read from the posting. The full description is below.

From the plant jobs report · week of October 19, 2026

Reliability Engineer roles in Massachusetts: typical posted base $97k–$132k. This one lists $147k–$184k.

Median of the low and high ends of 8 live postings that list pay, out of 12 reliability engineer openings in Massachusetts, read from manufacturers' own careers sites.

Massachusetts plant jobs report →Pay by team and state →What moves pay →

How this role compares

Against 11 other live reliability postings in Massachusetts.

Base pay: About 47% above similar roles
Experience asked: More than usual (10+ vs 8+)

Skills these teams ask for most

✓ Root cause 67%
✓ Tooling 67%
✓ Automation 50%
✓ New product launch 42%
Lean 42%
✓ Validation (IQ/OQ/PQ) 33%

✓ = this posting asks for it too. % = share of similar postings that mention it.

Stands out: this posting asks for SPC, MSA / Gage R&R, FDA / GMP, which few similar roles mention. If you have it, lead with it.

It asks for 10+ years. If you're close, apply anyway: requirements are a wish list. Talk to someone doing this work there first.

At a glance

Lifts up to 30 lbs

Pulled from the posting text. If it's not listed here, the posting didn't say.

How to get in at this plant

Five moves over a week or two. The first one takes ten minutes.

1
Pick 2–3 people on the Reliability team at TransMedics
Engineers who joined in the last year or two reply the most. Use the team search on this page to find them.
2
Send a short, curious note
One real question about their work. No favors yet. Each person gets a different note, written for this role.
3
Turn a reply into a short call
Questions worth asking about this team:
- What does a normal week look like on your team?
- How did you land the job? What stood out in your interviews?
4
Apply with someone vouching for you
If the call went well, ask whether they’d pass your résumé to the hiring manager. Send your résumé link, apply that day, and let them know.
5
Bring proof to the interview
One page of before-and-after numbers from projects you led: scrap, OEE, cycle time, cost. Plant managers hire on results.

This plant: TransMedics in Andover

1 other open role at this site.

Shipping & Receiving / Inventory Control Specialist · Controls · Specialist

Full description from TransMedicsAs posted on their careers site.Show

Position summary

The Principal NPI Manufacturing Engineer, Electromechanical Systems serves as the technical project leader for NPI manufacturing activities, driving the development, design transfer, manufacturing readiness, and commercialization of TransMedics OCS products.

This role will have a particular focus on integrated electromechanical equipment incorporating mechanical, electrical/electronic, and software-controlled components. The Principal Engineer will provide technical leadership across new product introduction activities involving capital medical equipment, consoles, diagnostic or imaging systems, and other complex electromechanical devices while ensuring robust, scalable, compliant, and manufacturable product designs and processes.

requirements

are met.

✓Provide manufacturing engineering expertise related to PCB/PCA assemblies, electrical and electronic components, wiring and cabling, sensors, motors and pumps, displays/HMIs, and hardware/software interfaces.
✓Lead and support system-level troubleshooting, root-cause and failure analysis, functional testing, manufacturing test equipment development, calibration activities, and hardware reliability assessments during new product introduction and manufacturing scale-up.
✓Develop and optimize manufacturing processes for integrated electromechanical assemblies, subassemblies, and final system-level builds.
✓Establish and track Key Performance Indicators (KPIs) and process capability metrics using statistical tools and methodologies such as MSA, GR&R, SPC, and related process capability techniques.
✓Represent TransMedics internally and externally as a manufacturing subject matter expert (SME), ensuring effective technical communication and knowledge transfer to production teams, suppliers, and cross-functional stakeholders.
✓Provide day-to-day technical leadership and direction across assigned NPI workstreams.
✓Mentor and guide junior engineers and technical staff, fostering a culture of engineering rigor, accountability, problem solving, and innovation.
✓Perform other TransMedics tasks and duties as required.

Responsibilities

◆This position will not have direct people-management responsibilities.
◆The position will provide technical leadership, mentoring, and workstream direction to engineers and other technical team members supporting assigned NPI programs.

Qualifications

✓BS in Mechanical Engineering, Electrical Engineering, Electromechanical Engineering, Mechatronics, Biomedical Engineering, or a related engineering discipline required.
✓10+ years of progressive engineering experience in an FDA/ISO-regulated medical device or medical equipment manufacturing environment.
✓Extensive experience in NPI Manufacturing, Process Development, Design Transfer, DFM/DFA, PFMEA, manufacturing validation, and commercialization of medical devices or medical equipment.
✓Direct experience supporting the development and manufacturing introduction of capital medical equipment, consoles, diagnostic systems, imaging systems, robotics, or similar integrated electromechanical devices.
✓Demonstrated experience working with complex systems incorporating mechanical, electrical/electronic, and software-controlled components.
✓Hands-on experience with PCB/PCA assemblies, electrical/electronic components, wiring and cabling, sensors, motors/pumps, displays/HMIs, and hardware/software interfaces.
✓Demonstrated experience with system-level troubleshooting, root-cause and failure analysis, functional testing, manufacturing test equipment, calibration, and hardware reliability.
✓Proven leadership in the selection, qualification, implementation, and scale-up of manufacturing equipment, tooling, fixtures, and automation.
✓Demonstrated ability to lead complex technical NPI projects from product development through design transfer, manufacturing scale-up, and commercial production.
✓Strong project leadership skills, with demonstrated accountability for technical planning, execution, cross-functional coordination, and delivery of NPI milestones.
✓Ability to remain technically hands-on while simultaneously providing strategic direction and leadership across complex engineer

Show full description ↓

This position is responsible for, but not limited to, the following

•Provide strategic oversight of manufacturing readiness for new product introductions, ensuring alignment of engineering resources, project schedules, technical requirements, and cross-functional deliverables.
•Serve as a technical leader for the manufacturing introduction and commercialization of complex medical equipment incorporating mechanical, electrical/electronic, and software-controlled components.
•Lead cross-functional collaboration with Product Development, Quality, Regulatory, Supply Chain, Manufacturing Operations, and other engineering teams to ensure robust, scalable, and compliant manufacturing processes.
•Coordinate, identify, develop, and implement advanced manufacturing processes to ensure production capacity, efficiency, cost-effectiveness, product quality, and adherence to applicable regulatory requirements.
•Define project plans, timelines, technical workstreams, and resources required to support NPI manufacturing programs, ensuring accountability for milestones and deliverables.
•Apply in-depth technical expertise to specify, design, develop, qualify, and validate manufacturing equipment, tooling, fixtures, automation, and manufacturing test equipment.
•Drive Design for Manufacturing and Assembly (DFM/DFA), PFMEA, Design Transfer, process development, and manufacturing validation activities to establish capable, efficient, and risk-mitigated manufacturing processes.
•Develop manufacturing assembly and functional test methods that ensure Critical to Quality (CTQ) and Critical to Assembly (CTA)

Physical attributes

•Office and manufacturing environment.
•Ability to lift up to 30 pounds.