Manager, Operational Excellence CAR T

Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson, and Legend Biotech USA Inc., have entered into a global, strategic collaboration to develop, manufacture, and commercialize a chimeric antigen receptor (CAR) T-cell therapy. This innovative strategic partnership is designed to combine the strengths and expertise of two companies to advance the promise of an immunotherapy CAR T platform and investigational treatment

The Operational Excellence Manager is responsible for working with business partners to identify improvement opportunities and assess, develop and implement improvement project plans across the site. Also supports the deployment of the Continuous Improvement programs and ensures projects and initiatives meet customer and company

by providing technical and business program leadership. This role supports the Business Partners to act as a change agent in driving continued operational excellence in the organization. The person will be responsible for the establishment and implementation of standard processes to ensure performance targets are met as it relates to Continuous Improvement. The Operational Excellence Manager will employ process excellence methodologies to bring value to the customer and drive ‘Right the First Time’ mentality. The incumbent supports project leads and project teams in developing program schedules and tactical implementation plans to meet overall program targets. Responsible for providing leadership in the tactical approach, deployment & execution of Process Excellence (Six Sigma, Lean & Design Excellence) in partnership with production leadership & the PE team. The person evaluates potential business impact for improvement projects and advises on their implementation.

The Operational Excellence Manager CAR-T will lead and drive continuous improvement initiatives across the organization, applying Lean principles, JJPS, Value Stream Mapping (VSM), Kaizen, and structured root-cause problem solving to improve quality, flow, productivity, cost, and overall operational performance. This role will partner cross-functionally with Operations, Quality, Engineering, Supply Chain, and other key stakeholders to identify improvement opportunities, eliminate waste and bottlenecks, implement high-impact CIP and strategic programs, and ensure measurable and sustainable business results.

The role will also be responsible for building Operational Excellence capabilities and strengthening a culture of continuous improvement through coaching, Lean/Six Sigma belt development, talent development, and problem-solving facilitation. The Manager will support performance management through tiered daily management, site scorecards, critical metric monitoring, Gemba, and corrective action management, while helping leaders translate business priorities into clear actions, accountability, and sustainable performance improvements.

• ◆Responsible for all JJPS business processes, lean leadership and the Culture of Excellence at the site.
• ◆Value Stream Mapping – Responsible to Maps site capabilities, identifies gaps, and delivers reliability improvements for all strategic brands.
• ◆CIP Pipeline Process - This person is the owner for the CIP pipeline process, yearly site CIP targets, support business planning/financial cycles, lead the site cost improvement portfolio in Planisware, and the CIP site important metric.
• ◆Site Performance Management Process - Leads the performance management cadence, execution & prepares site performance review decks for external platform reporting. Leads and manage the Performance management processes through all site tiers.
• ◆Lead Key Site/Global Programs - Executes key OPEX Strategic Initiatives and programs such as Smart Change Over & OEE Program, Golden Ba